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Team 5: HIV pathogenesis and Immunosenescence -


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Laveran's Staff:


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Head: Victor Appay

HIV pathogenesis and Immunosenescence

Principal research themes:

HIV pathogenesis and Immunosenescence group:

  • CD8+ T cell correlates of efficacy in HIV infection
  • Parallel between HIV infection and human aging
  • Collateral damages of immune activation and inflammation
  • T cell differentiation and renewal
  • T cell based therapy and vaccines
Immunobiology of Antigen presentation group:
  • Interactions of HIV with antigen presenting cells
  • Dissecting antigen presentation pathways
  • Influence of pathogen sensing on the regulation and quality of antigen presentation
  • Role of APOBEC-3G in the induction of HIV-specific T cell responses
  • Immunogenicity of vaccine candidates